Figure 4
From: Sensory involvement in the SOD1-G93A mouse model of amyotrophic lateral sclerosis
Transmission electron microscopic examination on VR and DR of hSOD1-G93A mice and their littermates. 4000×. A and A1: normal axon and myelin sheath. B and B1: showing numerous vacuoles and swollen mitochondria in the axoplasm; C, C1 and D1: indicating collapse and degradation of myelin sheath with condensed or absent axon in the central part; D shows a macrophage-like cell within the myelin sheath occupying the axon. The data are representative of all animals examined, at least 3 animals in each group.
