Table 1 Number of spinal cord neurons in mice with and without expression of hSOD1-G93A.

From: Sensory involvement in the SOD1-G93A mouse model of amyotrophic lateral sclerosis

  1. Lumbar enlargements were harvested from hSOD1-G93A mice at end stage and their non-transgenic littermates at the same age. There were 3 animals in each group and 12~15 sections were counted from each animal. Transversal sections (20 µm) were cut on a Leica VT 1000S vibratome. Motor neurons and sensory neurons were identified by immunohistochemical staining with SMI-32 and calretinin respectively. SMI-32-stained neurons in the ventral horn with a diameter of ≥25 µm were counted as motor neurons. Calretinin-positive neurons in the dorsal horn were counted as sensory neurons. Each value is a mean ± SD. *P < 0.05 vs Littermate.
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