Figure 10

Effects of PD 98059 and/or SB 203580 on H2O2-induced ERK phosphorylation. Serum-starved cells were pretreated with PD 98059 (10 µM) and/or SB 203580 (1 and 5 µM) for 30 min and then treated with HGF (10 ng/ml) for 15 min. ERK activation was evaluated by Western blot analysis. Representative data from 3 independent experiments were shown.