Figure 9 | Experimental & Molecular Medicine

Figure 9

From: Reactive oxygen species regulate the generation of urokinase plasminogen activator in human hepatoma cells via MAPK pathways after treatment with hepatocyte growth factor

Figure 9

Effect of PD 98059 or SB 203580 on HGF-mediated up-regulation of uPA. Serum-starved cells were pretreated with or without H2O2 (100 µM) for 30 min and then treated with PD 98059 (5 and 10 µM) or SB 203580 (1 and 5 µM). After incubation for 24 h, uPA in culture media was measured by Western blot analysis. Representative data from 3 independent experiments were shown.

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