Figure 5
From: Involvement of GADD153 and cardiac ankyrin repeat protein in cardiac ischemia-reperfusion injury
GADD153 induction was followed by transcriptional downregulation of CARP in the area of IR injury. Induction of GADD153 mRNA was detected by RT-PCR in the area with 30 min ischemic injury (IR), compared to the area with non-ischemic injury (N) in the rat heart. Downregulation of CARP mRNA in the area with 45 min ischemic injury (IR), compared to the area with non-ischemic injruy (N) in the rat heart. Representatives of at least three independent experiments are shown. Relative fold induction after normalization to GAPDH mRNA (right panel). Values are means ± SEM. Sham, sham operation; Exp, experiment.
