Figure 1

Effect of AGEs and statin on proliferation of RASMCs. Proliferation was increased with AGEs treatment dose-dependently (A) and decreased with statin dose-dependently (AGE 50 µg/ml) (B). Cell proliferation was determined by MTT assay. Data are expressed as mean ± SEM (n = 5). *P < 0.05 versus control; †P < 0.05 versus AGEs. CTL, control; AGEs, advanced glycation endproducts.