Figure 2

Effect of AGEs and statin on formation of intracellular ROS in RASMCs. Results shown are increased oxidative stress with AGEs treatment dose-dependently (A) and suppressive effect of statin on oxidative stress (AGE 50 µg/ml) (B). Data are expressed as mean ± SEM (n = 5). *P < 0.05 versus control; †P < 0.05 versus AGEs. CTL, control; AGEs, advanced glycation endproducts.