Figure 3 | Experimental & Molecular Medicine

Figure 3

From: Potential role of HMG CoA reductase inhibitor on oxidative stress induced by advanced glycation endproducts in vascular smooth muscle cells of diabetic vasculopathy

Figure 3

Effect of statin on activation of NFκB p65 in RASMCs treated with AGEs. Western blot for β-actin is shown as a protein loading control. Compared to cells treated with AGEs alone, cells treated with statin demonstrated significant inhibition of NFκB p65 expression. Symbols - and + indicate the absence and presence of AGEs or simvastatin, respectively. Data show a representative gel of NFκB p65 products and a bar graph of data quantitated as relative expression (a.u.) over respective control (mean ± SEM) (n = 5). *P < 0.05 versus control, †P < 0.05 versus AGEs-treated. AGEs, advanced glycation endproducts

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