Figure 7 | Experimental & Molecular Medicine

Figure 7

From: Potential role of HMG CoA reductase inhibitor on oxidative stress induced by advanced glycation endproducts in vascular smooth muscle cells of diabetic vasculopathy

Figure 7

H&E staining and immunohistochemistry for COX-2 of sections of carotid artery from controls and AGEs- and statin-treated rats. The statin-treated model (C) showed similar intimal thickness to controls (A) but more reduced neointimal hypertrophy than those not treated (B) (×100, H&E staining). COX-2 staining was more abundant in lesions from AGEs-treated model (E) than controls (D) or statin treated (F). Immunohistochemical analysis of the carotid artery stained (×200) with specific antibodies for COX-2.

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