Figure 1
From: S-Adenosyl-L-methionine ameliorates TNFα-induced insulin resistance in 3T3-L1 adipocytes

Effects of SAM on glucose transport in TNFα treated 3T3-L1 adipocytes. Cells were treated with SAM (1 mM) and TNFα (50 ng/ml) for 72 h and incubated with or without insulin (100 nM) for 30 min. Glucose transport levels seen in the cells not treated with SAM, TNFα or insulin (control) was expressed as 100 and the others were expressed as its relative values. *P < 0.001 compared to the control, †P < 0.001 compared to the level of cells treated with insulin and not TNFα, **P < 0.001 compared to the level of cells treated with TNFα and not but SAM. ‡P < 0.001 compared to cells treated with insulin and TNFα.