Figure 4 | Experimental & Molecular Medicine

Figure 4

From: Bilirubin protects grafts against nonspecific inflammation-induced injury in syngeneic intraportal islet transplantation

Figure 4

Infiltration of Kupffer cells and insulin production by islets in situ. Representative illustrations were taken from livers of vehicle (A, C) or bilirubin (B, D)-treated diabetic rats receiving intraportal injection of 1000 IEQ islets/rat and harvested 24 h (A, B) or 10 days (C, D) later. Each group had 10 rats, five of which were randomly sacrificed 24 h or 10 days after transplantation. The liver sections were immunostained with an anti-CD68 Ab to detect Kupffer cells (A, B), or an anti-insulin Ab to detect insulin (C, D). Brown color indicates positive cells.

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