Figure 1 | Experimental & Molecular Medicine

Figure 1

From: Association of Paraoxonase 1 (PON1) polymorphisms with osteoporotic fracture risk in postmenopausal Korean women

Figure 1

Gene maps, haplotypes, and linkage disequilibrium (LD) coefficients of PON1. (A) Polymorphisms identified in PON1 on chromosome 7q21.3. Coding exons are marked with black rectangles, and 5'- and 3'-UTRs with white rectangles. The first base of the translation start site is denoted nucleotide '+1'. Asterisks indicate SNPs that were genotyped in a larger population (n = 1,329). The frequencies of SNPs that were not subjected to larger-scale genotyping are based on sequence data (n = 24). (B) LD blocks and correlation coefficients among PON1 polymorphisms. Red squares indicate statistically significant allelic association between the pair of SNPs, as measured by the D' statistic; darker shades of red indicate higher values of D', up to a maximum of 1. (C) Haplotype frequencies of PON1 polymorphisms.

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