Figure 1

Hydroxydibenzoylmethane (HDB) promoted HL-60 cell apoptosis. (A) Chemical structure of HDB. (B) The cells were treated with different concentrations of HDB at 12 h. Cell viability was determined by the trypan blue exclusion assay. (C) DNA fragmentation was detected by gel electrophoresis following 0, 10, 50 and 100 µM HDB stimulation for 12 h, and 50 µM at 0, 6, 12 and 24 h. M, DNA ladder maker. Data were representative of at least three experiments.