Figure 4 | Experimental & Molecular Medicine

Figure 4

From: Benzoxathiol derivative BOT-4-one suppresses L540 lymphoma cell survival and proliferation via inhibition of JAK3/STAT3 signaling

Figure 4

BOT-4-one affects cancer cell survival and proliferation. L540 (A and C) and DG-75 (B and D) cells were treated with either vehicle (DMSO) alone or BOT-4-one and incubated for the indicated time periods. Total and viable cell numbers were counted by trypan blue exclusion assay. The cell viability and proliferation of L540 cells were decreased by BOT-4-one in a dose- and time-dependent manner, but DG-75 cells were not affected, where JAK/STAT3 signaling was not activated. Results are shown as the mean of three independent experiments (± SD indicated by error bar). *P < 0.001; **P < 0.05, significant difference when the value of treatment was compared to that of the control.

Back to article page