Figure 4

Effect of DDS on PQ-induced NADPH oxidase 4 mRNA expression in mouse lung tissue. Total mouse lung RNA was prepared and analyzed by RT-PCR using primers specific for NOX2 and NOX4 mRNA. Target gene expression levels were normalized to the β-actin signal. Quantified data (n = 3) are presented in bar graphs (lower panel). ^#P < 0.005 vs. control mice (CC); ^*P < 0.005 vs. PQ-treated mice (PQ).