Figure 2
From: Grape seed proanthocyanidin extract ameliorates monosodium iodoacetate-induced osteoarthritis
Osteoclastic activity and osteophyte formation for 4 weeks after MIA injection. Bone and osteophyte formation was evaluated in the hematoxylin and eosin-stained, paraffin-embedded knee joint sections and micro-CT analysis of the MIA injected rats treated with GSPE or vehicle, respectively. (A) Osteoclast generation was assessed using hematoxylin and eosin. The bar graphs represent the mean values ± SD of the cells that stained positive (original magnification × 200). **P < 0.01 compared with the MIA injection group. (B) Osteophyte analysis using Micro-CT.
