Figure 6
From: Grape seed proanthocyanidin extract ameliorates monosodium iodoacetate-induced osteoarthritis

Immunohistochemical analysis of the IL-1β and nitrotyrosine expressions after treatment with GSPE in the MIA-induced arthritis models at 4 weeks after MIA injection. The positive cells are brown; the nuclei were counterstained with hematoxylin. The slides of the representative sections showed the expression of IL-1β or nitrotyrosine (original magnification × 400).