Figure 5

Epithelial regeneration in full-thickness skin wounds at 12 days after treatment with PRP + various delivery systems. (A) Immunohistochemical staining with anti-involucrin antibodies of treated wound sections. Red and blue (DAPI) indicate differentiated epithelial layer and nucleus, respectively. Scale bars indicate 100 µm. (B) RT-PCR analysis for MMP-9 expression in the wounds at 12 days after treatment with PRP + various delivery systems.