Figure 5

Immunohistochemical changes of glomerular transforming growth factor-beta1 (TGF-β1). (A) Representative photomicrographs showing immunohistochemical staining of the glomerulus. × 400. (B) Immunodetectable TGF-β1, which was expressed in glomerular podocytes, was markedly decreased in the diabetic control group compared to the control LETO group. However, in the control group that was treated with FA, TGF-β1 expression was effectively restored. CON, control group; DM, diabetic group; FA, ferulic acid treated diabetic group. ^*P < 0.05 compared with CON, ^†P < 0.05 compared with DM.