Figure 2 | Experimental & Molecular Medicine

Figure 2

From: Relationship between ganglioside expression and anti-cancer effects of the monoclonal antibody against epithelial cell adhesion molecule in colon cancer

Figure 2

HPTLC profiles of Gangliosides in SW620 colon cancer cells treated with EpCAM mAb and RAW264.7 cells. (A) Qualitative analysis of gangliosides in SW620 cells, and ganglioside extracts were resolved by HPTLC. Lanes 1 and 2, ganglioside standard markers (M1 and M2); lane 3, SW620 colon cancer cells (control); lane 4, SW620 colon cancer cells treated with RAW264.7 cells; lane 5, SW620 colon cancer cells treated with EpCAM mAb; lane 6, SW620 colon cancer cells treated with EpCAM mAb and RAW264.7 cells. (B) Quantitative analysis of gangliosides (GM1 and GD1a) expression in SW620 colon cancer cells treated with EpCAM mAb and RAW264.7 cells. The Quantitative values from densitometry program (Beta 4.0.3 of Scion Image, Frederick, MD). Similar observations were made in 3 separate experiments.

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