Figure 5 | Experimental & Molecular Medicine

Figure 5

From: Parthenolide-induced apoptosis of hepatic stellate cells and anti-fibrotic effects in an in vivo rat model

Figure 5

Effects of NAC and BSO in PT-treated RI-T cells. (A) Cell growth inhibition was assessed using MTT assays. (B) Annexin-V-positive cell numbers were determined using a FACStar flow cytometer. Graphs show percentages of annexin-V-positive cells. (C) Intracellular O2•- (DHE) levels. (D) Intracellular GSH levels. Graphs show levels of the mean DHE fluorescence of C and of the mean CMF fluorescence of D. *P < 0.05 versus the control group. **P < 0.05 versus the PT 10 µM group.

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