Figure 1 | Experimental & Molecular Medicine

Figure 1

From: A functional comparison between the HER2high/HER3 and the HER2low/HER3 dimers on heregulin-β1-induced MMP-1 and MMP-9 expression in breast cancer cells

Figure 1

The levels of expression of MMP-1 and MMP-9 mRNA and protein were increased by HRG in breast cancer cells. After serum-starvation for 24 h, MCF7 cells were treated with HRG at the indicated concentrations for 24 h. MMP-1 and MMP-9 protein and mRNA expression was determined by (A) Western blotting (upper band) and Zymography (lower band) and (B) RT-PCR, respectively. The results shown are representative of three independent experiments. Con, control; HRG, heregulin-β1.

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