Figure 2
From: Cyclooxygenase-2 inhibitors modulate skin aging in a catalytic activity-independent manner
NS-398 increases but celecoxib and aspirin decrease epidermal thickness in hairless mice. NS-398 (A), celecoxib (B) and aspirin (C) were treated to the right and left side of dorsal skin of mice for 12 weeks. Paraffin sections of the skin were stained with H & E and then epidermal thickness was measured. Data represent means ± S.E. (n = 10). *P < 0.05 and **P < 0.01; compared with the corresponding vehicle-treated group. (D) Representative images of H & E staining were shown.
