Figure 1
Effects of enchinomycin on ovarian ovulation in rats. After PMSG priming for 48 h, immature rats were treated with hCG to induce ovulation. (A) In a set of enchinomycin dose dependent experiments, rats were injected with either vehicle (dimethylsulfoxide) or various dose of enchinomycin (0.01, 0.1, 1 or 10 mg/kg body weight) at 6 h after hCG. (B) In another treatment time dependent experiments, rats were given either vehicle or a fixed dose of enchinomycin (1 mg/kg body weight) at 3, 6, 9 or 10 h after hCG. The ovulated eggs were counted at 20 h after hCG, and their numbers were compared between the enchinomycin-treated or untreated groups. Each value represents the means ± SE. One-way analysis of variance (ANOVA) was used to analyze the data. Different superscripts denote significant values (P < 0.05) by Tukey's multiple-range test.
