Figure 3 | Experimental & Molecular Medicine

Figure 3

From: PPARγ modulates vascular smooth muscle cell phenotype via a protein kinase G-dependent pathway and reduces neointimal hyperplasia after vascular injury

Figure 3

Rosiglitazone (RSG) increases the expression level of protein kinase G (PKG) Iα, but not PKG Iβ. Western blot showed that platelet-derived growth factor (PDGF) treatment reduced the total amount of PKG I and that this effect of PDGF was blocked by RSG. Interestingly, PDGF treatment changed the level of PKG Iα, but not that of PKG Iβ. These results suggest that RSG regulates the expression of PKG Iα, but not PKG Iβ. n=4.

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