Figure 5

Expression of miR-30a, miR-30e and miR-19b in atherosclerotic and normal aortic tissues were evaluated by TaqMan quantitative reverse-transcription PCR (qRT–PCR), revealing downregulation of these microRNAs (miRNAs) in apolipoprotein E knockout (apoE−/−) aortic tissues compared with levels observed in B6 control aortic tissues. The expression values for the B6 controls were set at 1. Data are indicated as means±s.d. of seven individual subjects; *P<0.05 versus B6 controls.