Table 1 Subject characteristics

From: Identification of a genetic locus on chromosome 4q34-35 for type 2 diabetes with overweight

 

Linkage study

Association study

 

SNUH

SNUH

KHGS

Characteristic

T2DM (all)

T2DM (BMI23)

T2DM (all)

NC (all)

T2DM (BMI23)

NC (BMI23)

T2DM (all)

NC (all)

T2DM (BMI23)

NC (BMI23)

Number of subjects

386 (269 Pairs, 171 families)

216 (132 Pairs, 101 families)

378

382

282

129

949

932

835

491

Sex (M/F)

170/216

93/123

181/197

191/191

136/146

54/75

479/470

447/485

414/421

194/297

Age (years)

56.51

56.77

61.44

64.79

60.82

63.94

57.17

64.13

56.04

63.91

BMI (kg m−2)

24.60±3.00

26.20±2.34

24.87±2.92

22.36±3.00

26.03±2.30

25.58±2.33

26.03±3.08

23.34±3.05

26.70±2.57

25.62±2.08

WHR

0.90±0.06

0.91±0.05

0.91±0.06

0.89±0.06

0.92±0.05

0.92±0.06

0.92±0.06

0.91±0.07

0.93±0.06

0.94±0.06

Fasting insulin (mg dl−1)

11.91±15.32

11.66±6.97

12.70±10.57

7.22±3.41

13.80±11.53

8.79±3.50

8.80±5.89

7.22±6.91

9.11±6.00

8.05±7.65

  1. Abbreviations: BMI, body mass index; KHGS, Korean Health and Genome Study; NC, normal controls; SNUH, Seoul National University Hospital; T2DM, type 2 diabetes mellitus; WHR, waist-to-hip ratio.