Figure 1
From: Mesenchymal stem cells: environmentally responsive therapeutics for regenerative medicine
Pericytes are stimulated by soluble growth factors and chemokines to become activated MSCs, which respond to the microenvironment by secreting trophic (mitogenic, angiogenic, anti-apoptotic or scar reduction), immunomodulatory or antimicrobial factors. After the microenvironment is re-established, MSCs return to their native pericyte state attached to blood vessels.1
