Table 1 MSC and CFU-F concentrations and frequency derived from adult and near-fetal tissues

From: Mesenchymal stem cells: environmentally responsive therapeutics for regenerative medicine

Human tissue source

Native CFU-F concentration range per ml of fluid/tissue

MSC frequency range (CFU-F/10 6 nucleated cells)

References

Bone marrow aspirate

109–664a

10–83

91, 183, 184, 185, 186, 187

Adipose/lipoaspirate

2058–9650

205–51 000

98, 184, 188, 189, 190

Dermis

Not reported

74 000–157 000

89

Umbilical cord blood

0.06

0–0.02

184, 185, 191, 192

Peripheral blood

0

0–2b

185, 192, 193

Synovial fluid

4–14

2–250

92, 194

Amniotic fluid

3

9.2

195

  1. aBased on average of 8 × 106 nucleated cells per ml bone marrow aspirate.183
  2. bOccurance of CFU-F in peripheral blood requires systemic treatment with GCSF.
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