Table 2 The NAS between HFD and Chow groups over time

From: Oleuropein prevents the progression of steatohepatitis to hepatic fibrosis induced by a high-fat diet in mice

 

Fibrosis (n)

Total period (month)

Name

n

Steatosis grade (0–3)

Lobular inflammation (0–3)

Ballooning (0–2)

NAS score (0–8)

0

1A

1B

1C

2

3

3

Chow

2

0.0±0.0

0.0±0.0

0.0±0.0

0.0±0.0

1

1

0

0

0

0

 

HFD

4

1.0±1.4

0.3±0.5

0.0±0.0*

1.3±1.9

2

1

0

1

0

0

6

Chow

4

0.5±0.6

0.3±0.5

0.0±0.0

0.8±1.0

3

0

0

1

0

0

 

HFD

4

2.5±0.6*

1.5±0.6*

1.0±0.0*

5.0±0.8*

0

0

1

2

1

0

9

Chow

4

0.5±0.6

0.0±0.0

0.0±0.0

0.5±0.6

2

2

0

0

0

0

 

HFD

4

3.0±0.0*

1.8±0.5*

1.8±0.5*

6.5±1.0*

0

0

2

0

2

0

12

Chow

4

0.3±0.5

0.0±0.0

0.3±0.5

1.0±1.2

2

1

0

1

0

0

 

HFD

4

2.8±0.5*

2.8±0.5*

1.8±0.5*

7.3±1.0*

0

0

0

0

0

4

  1. Abbreviations: Chow, regular diet; HFD, high-fat diet; NAFLD, non-alcoholic fatty liver disease; NAS, NAFLD activity score.
  2. *P <0.05 vs Chow group.
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