Figure 1
From: CDK5-dependent inhibitory phosphorylation of Drp1 during neuronal maturation
Enrichment of Drp1 and phosphorylated Drp1S616 in post-mitotic mature neurons. (a–l) Immunohistochemical labeling of Drp1 (a, g, g′), phosphorylated Drp1S616 (pDrp1S616; b, h, h′) and their merged image (c, i, i'), or NeuN (d, j) and pDrp1S616 (e, k) of embryonic (E18.5; a–f) and adult (g–l) rat cerebral cortex. (g″, h″, i″) Immunohistochemical labeling without antibodies against Drp1 and pDrp1S616 as negative controls. CP, cortical plate; IZ, intermediate zone; MZ, marginal zone; SP, subplate. (m) Immunoblot of Drp1 and pDrp1S616 in embryonic (E18), post-natal (P1), and adult rat cerebral cortex.
