Table 2 CTCF-binding partners
From: CTCF as a multifunctional protein in genome regulation and gene expression
Binding proteins | Description | Reference |
|---|---|---|
LS Pol II | The largest subunit of RNA polymerase II is highly co-localized with CTCF in the nucleus and interacts with CTCF both in vitro and in vivo | |
Vigilin | Vigilin is a recently identified protein partner of CTCF that binds a number of known CTCF-target sites, and the CTCF–vigilin complex regulates Igf2/H19 expression | |
Kaiso | The transcription factor Kaiso localizes to the nucleus and, like CTCF, is ubiquitously expressed. Its POZ domain interacts with CTCF and negatively regulates CTCF’s insulator activity |
