Figure 2
From: Pycnogenol attenuates atherosclerosis by regulating lipid metabolism through the TLR4–NF-κB pathway
PYC abrogated LPS-induced foam cell formation. Human THP-1 monocytes were stimulated with the indicated doses of PYC prior to incubation with 10 μg ml−1 LPS. After exposure to oxidized LDL (CuoxLDL) for 10 h, Oil Red O staining was used to label the foam cells (a). The ratio CE/TC was introduced to assess the lipid accumulation (b). The triglyceride content in cells was detected by enzymatic colorimetric assays (c). **P<0.01 versus control group; #P<0.05 versus LPS-pretreated cells. ##P<0.01.
