Figure 1 | Experimental & Molecular Medicine

Figure 1

From: A polymorphic minisatellite region of BORIS regulates gene expression and its rare variants correlate with lung cancer susceptibility

Figure 1

Gene expression and methylation status of the 5′ flanking non-coding region of BORIS. (a) Gene expression of BORIS in tumor tissues (T1–T10) of lung cancer patients. (b) Results of bisulfite sequencing analysis of a CpG island in the 5′ flanking region of BORIS in tumor tissues (T) and lung cancer cells (H1299 cells and H1299 cells treated with 1 and 5 μM 5-azad-C). Open circles (○) indicate non-methylated CpG; filled circles (•) indicate methylated CpG; percentages indicate the ratio of methylation.

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