Table 3 The frequency of rare Boris-MS2 alleles in controls and lung cancer cases

From: A polymorphic minisatellite region of BORIS regulates gene expression and its rare variants correlate with lung cancer susceptibility

  

Common alleles

Rare alleles

  
 

No. of alleles

14

15

Total

10

13

16

17

18

Total

OR (95% CI)

P-value

Controls

 Male

652 (%)

392 (60.1)

250 (38.4)

642 (98.5)

1

2

2

1

4

10 (1.5)

1 (reference)

 Female

528 (%)

331 (62.7)

187 (35.4)

518 (98.1)

4

4

1

0

1

10 (1.9)

1 (reference)

 Total

1180 (%)

723 (61.3)

437 (37.0)

1160 (98.3)

5

6

3

1

5

20 (1.7)

1 (reference)

 

Lung cancer cases

 Male

342 (%)

219 (64.0)

113 (33.0)

332 (97.0)

1

5

3

0

1

10 (3.0)

1.93 (0.80–4.69)

0.138

 Female

70 (%)

47 (67.2)

19 (27.1)

66 (94.3)

1

2

0

0

1

4 (5.7)

3.14 (0.96–10.29)

0.047*

 Total

412 (%)

266 (64.6)

132 (32.0)

398 (96.6)

2

7

3

0

2

14 (3.4)

2.04 (1.02–4.08)

0.039*

  1. Abbreviations: CI, confidence interval; OR, odds ratio. *P<0.05.