Figure 6
From: Crucial role of HMGA1 in the self-renewal and drug resistance of ovarian cancer stem cells
HMGA1 overexpression enhances the drug resistance of ovarian cancer cells in a xenograft tumor model. (a) Tumor size was measured on the indicated day after the subcutaneous injection of HMGA1-overexpressing A2780 or control A2780 cells into nude mice (1 × 105 per injection) with HBSS or paclitaxel treatment (n=6). Paclitaxel was injected at each data point. *P<0.05. (b) Immunohistochemistry results of tumors harvested on day 45. DAPI and the indicated antibodies are shown. Scale bar, 50 μm.
