Figure 6 | Experimental & Molecular Medicine

Figure 6

From: Cadmium-induced ER stress and inflammation are mediated through C/EBP–DDIT3 signaling in human bronchial epithelial cells

Figure 6

Effect of DDIT3 knockdown on the inflammatory response to Cd in primary normal human bronchial epithelial (NHBE) cells. Expression levels of C/EBP family members in cells treated with Cd (a). Expression levels of C/EBP target genes between Con and Cd. (b). Primary NHBE cells were transiently transfected with DDIT3 siRNA or non-targeting siRNA (siNC). After incubation for 24 h, the cells were treated with Cd (10 μM) for 24 h. Levels of pro-inflammatory cytokine mRNAs were analyzed by quantitative real-time PCR (c). All data shown are representative of at least three biological replicates. *P<0.05; **P<0.01, ***P<0.001.

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