Table 1 Basic characteristics of the CAD patients with low or high serum IL-33 levels

From: IL-33 promotes IL-10 production in macrophages: a role for IL-33 in macrophage foam cell formation

 

L-group (n=115)

H-group (n=114)

P-value

age (year)

64.31±(13.31)

65.86±(11.22%)

0.34

Male (n, %)

77 (66.96)

65 (57.05%)

0.12

Smoking (n, %)

48 (41.74%)

44 (38.60%)

0.63

LVEF (%)

64.36±8.10

62.53±10.32

0.14

IL-33 (pg ml−1)

24.25 (10.33, 56.67)

262.56 (144.75, 946.18)

<0.01*

TC (mmol l−1)

5.32±1.24

4.25±1.01

<0.01

LDL-c (mmol l−1)

3.42±0.97

2.48±0.90

<0.01

HDL-c(mmol l−1)

1.20±0.28

1.17±0.33

0.38

TG (mmol l−1)

1.48 (1.05, 2.34)

1.31 (1.03, 1.86)

0.15*

SBP (mm Hg)

153.43±32.76

158.24±29.81

0.25

DBP (mm Hg)

86.70±15.31

89.29±15.91

0.21

BMI (kg m−2)

23.56±2.60

23.59±3.21

0.93

DM (n, %)

31 (26.96%)

21 (18.42%)

0.12

hs-CRP (mg l−1)

2.90 (1.16, 7.92)

3.83 (1.72, 14.97)

0.06*

Serum creatine (μmol l−1)

100.17±19.27

103.97±20.47

0.15

Anti-platelets (n, %)

111 (96.52%)

113 (81.58%)

0.18

ACEI (n, %)

91 (79.13%)

93 (81.58%)

0.64

βRB (n, %)

78 (67.83%)

74 (64.91%)

0.64

Diuretics (n, %)

15 (13.04%)

14 (12.28%)

0.86

CCB (n, %)

50 (43.48%)

54 (47.37%)

0.55

Statins (n, %)

104 (90.43%)

100 (87.72%)

0.51

OAA (n, %)

25 (21.74%)

18 (15.79%)

0.26

  1. Abbreviations: ACEI, angiotensin converting enzyme inhibitor; BMI, body mass index; βRB, β-receptor blocker; CCB, calcium channel blocker; DBP, diastolic blood pressure; DM, diabetes mellitus; HDL, high-density lipoprotein cholesterol; H-group, patients with high serum IL-33 levels (>56.67 pg ml−1); hsCRP, high-sensitivity C-reactive protein; LDL, low-density lipoprotein cholesterol; L-group, patients with low serum IL-33 levels (⩽56.67 pg ml−1); LVEF, left ventricular ejection fraction; OAA, oral anti-diabetic agents; SBP, systolic blood pressure; TC, total cholesterol; TG, triglyceride.
  2. *P-values were derived from the Wilcoxon two-sample test.
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