Figure 2
From: Therapeutic inhibition of SGK1 suppresses colorectal cancer
SGK1 promotes colonic tumor cell proliferation and migration and inhibits 5-FU-induced cell apoptosis. (a) EdU assay of HCT116 cells upon treatment with SGK1 overexpression plasmids (SGK1) and SGK1 inhibitor (GSK650394); scale bars, 200 μm; n=4. (b) Cell cycle analysis of HCT116 cells by flow cytometry; n=4. (c) EdU staining of HT29 cells; scale bars, 200 μm; n=4. (d) Cell cycle analysis of HT29 cells; n=3. (e) Cell apoptosis analysis of HCT116 cells; n=4. (f) Transwell analysis of HCT116 cell migration; scale bars, 100 μm; n=4; ***P<0.001.
