Figure 2 | Experimental & Molecular Medicine

Figure 2

From: Rab25 augments cancer cell invasiveness through a β1 integrin/EGFR/VEGF-A/Snail signaling axis and expression of fascin

Figure 2

Rab25 induces β1 integrin expression. (a) MCF-7 cells were transfected with indicated vectors. Immunoblotting. (b) Cells were co-transfected with indicated vectors and siRNA prior to invasion assay (mean±s.d. ***P<0.001 versus control vector with scrambled siRNA, ###P<0.001 versus Rab25 overexpression with scrambled siRNA). (c) MCF-7 cells were transfected with indicated vector prior to invasion assay (mean±s.d.***P<0.001 versus control vector). (d, e) MCF-7 cells were co-transfected with indicated vectors and siRNAs. Immunoblotting. Representative results are presented from at least three independent experiments with similar results.

Back to article page