Figure 4 | Experimental & Molecular Medicine

Figure 4

From: Protection of nigral dopaminergic neurons by AAV1 transduction with Rheb(S16H) against neurotoxic inflammation in vivo

Figure 4

Increase in neuroinflammatory responses induced by pKr-2 treatment in the SN. (a) Double-immunofluorescence staining for TNF-α and IL-1β within Iba1-positive microglia in the SN at 1 day after pKr-2 treatment. CON, contralateral control side. Scale bars, 20 μm. (b, c) Western blot analysis of Iba1, TNF-α and IL-1β at 1 day after pKr-2 treatment in the SN. The density of Iba1, TNF-α, and IL-1β bands was normalized to the density of the β-actin band for each sample. *P<0.01 and **P<0.05 vs contralateral controls (one-way ANOVA and Tukey’s post hoc analysis; n=4, each experimental group). All values are expressed as the mean±s.e.m.

Back to article page