Figure 1 | Experimental & Molecular Medicine

Figure 1

From: Nucleophosmin modulates the alleviation of atopic dermatitis caused by the marine-derived compound dihydroaustrasulfone alcohol

Figure 1

Anti-inflammatory and anti-oxidative stress effects of WA-25 in LPS-stimulated macrophages after 16 h. (a) Western blot of iNOS from LPS-stimulated macrophages treated with 10 μM WA-25. The relative density of iNOS is shown in the graphs. (b) NO production from LPS-stimulated macrophages treated with 10 μM WA-25. (c) Reactive oxygen species (ROS) production from macrophages in the control, LPS and LPS+WA-25 groups. (d) Immunostaining of HO-1 (red) in macrophages in the control, LPS and LPS+WA-25 groups. (e) Western blot analysis of HO-1 and Nrf2 from LPS-stimulated macrophages treated with 10 μM WA-25. Relative densities of HO-1 and Nrf2 are shown in the graphs under the blots. *Significantly (P<0.05) different from the LPS-stimulated group. Scale bar=30 μm; n=6 per group.

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