Figure 4 | Experimental & Molecular Medicine

Figure 4

From: Nucleophosmin modulates the alleviation of atopic dermatitis caused by the marine-derived compound dihydroaustrasulfone alcohol

Figure 4

Downregulation of NPM blocks anti-inflammatory effects of WA-25. (a, b) Western blot of iNOS. Relative densities of the bands are provided. *Significantly (P<0.05) different from the LPS group. #Significantly (P<0.05) different from the L+WA-25+siRNA group; n=6 per group. (c) Photos of animals from different groups on day 15. (d) AD scores, (e) TEWL levels, (f) scratching behavior and (g) alloknesis of the groups. (h) NPM immunostaining in the skin. Scale bar=8 μm. (i) LAMP-1 immunostaining in the skin. Scale bar=50 μm. *Significantly (P<0.05) different from the AD+W group; n=6 per group. TEWL, transepidermal water loss.

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