Figure 6 | Experimental & Molecular Medicine

Figure 6

From: Inhibition of TNFα-interacting protein α (Tipα)-associated gastric carcinogenesis by BTG2/TIS21 via downregulating cytoplasmic nucleolin expression

Figure 6

Overall survival of gastric cancer is reciprocally regulated by the expression of BTG2/TIS21 and nucleolin. To explore the clinical significance and correlation between the survival of gastric cancer and expression of BTG2 and NCL, we examined the public databases concerning human gastric cancer. The red line indicates the high expresser, and the black one indicates the low expresser. Kaplan–Meier analysis showing the overall survival vs BTG2 and NCL expressions in gastric cancer patients. (a) Note the better survival rate in the poorly differentiated gastric cancer patients with BTG2 high expression than in those with BTG2 low expression (p=0.0024), whereas it was statistically insignificant in the well-differentiated gastric cancers. (b) By contrast, the NCL high expresser exhibited a lower survival rate in the poorly differentiated gastric cancers compared with the low expressers (p=0.033). The correlation was also statistically insignificant in the well-differentiated gastric cancers. The numbers indicate the surviving patients at each time point.

Back to article page