Figure 7
From: Sleep deprivation disrupts the lacrimal system and induces dry eye disease
The lacrimal neurotransmitter, secretory proteins and free amino-acid changes after sleep deprivation (SD). (a) Acetylcholine (ACH) and (b) dopamine (DA) concentrations in the lacrimal gland tissues were significantly decreased after SD, compared with the normal control (NC). (*P<0.05, **P<0.01, ***P<0.001, compared with the NC). (c) The lacrimal secretory-related genes were differentially expressed after SD. (d) There was a marked change in the levels of 34 free amino acids in the lacrimal gland tissues after SD. The data were transferred to the Z-score log 2-Fpkm and log 2-Concentration (μg g−1) by each row and clustered based on the Euclidean distance (n=3/group).
