Table 1 Characteristics and physiologies of IPF patients and normal individuals

From: MicroRNA-708-3p as a potential therapeutic target via the ADAM17-GATA/STAT3 axis in idiopathic pulmonary fibrosis

Characteristic

Normal

IPF

P-value

Number

78

78

/

Age (years)

67.9±7.5

68.1±6.8

/

Gender (Male/female)

59/19

54/24

/

FVC (% of predicted)

88.7±10.7

57.8±9.3

<0.01

TLC (% of predicted)

90.7±9.6

63.6±10.9

<0.01

DLCO (% of predicted)

85.8±5.3

57.2±4.9

<0.01

PaO2 (mm Hg)

89.7±4.6

67.2±5.9

<0.01

PaCO2 (mm Hg)

38.2±4.7

35.2±3.7

/

Smoking History (n)

49

51

/

  1. Abbreviation: DLCO, diffusing capacity for carbon monoxide; FVC, forced vital capacity; IPF, idiopathic pulmonary fibrosis; TLC, total lung capacity; smoking history denotes subjects with >5 years of cigarette smoking.