Figure 1
From: Microbiota in T-cell homeostasis and inflammatory diseases
Microbiota diversity is determined by environmental factors and signals to distal organs that contribute the development of diseases. The microbiota is established by other environmental factors, such as dietary fiber, saturated lipids, infection and antibiotics, and its colonization depends on the physiological condition of each tissue. Altered commensal microbiota in the gut or lung could influence the progression of various tissue-specific diseases through signal mediators, including microbes, microbial metabolites and circulating immune cells.
