Figure 7

Comparisons of the nerve cell markers and BrdU-positive cells among the NC, overexpressed miR-124 and si-PDXK groups. (a) Double-labeled positive cells (BrdU+NSE, BrdU+NF and BrdU+MAP2) detected by immunohistochemistry among the NC, overexpressed miR-124 and si-PDXK groups. (b) A comparison of the double-labeled positive cell density (BrdU+NSE, BrdU+NF and BrdU+MAP2) among the NC, overexpressed miR-124 and si-PDXK groups. (c) A comparison of the BrdU-positive cell density among the NC, overexpressed miR-124 and si-PDXK groups. (d) A comparison of the ratio of BrdU-positive cells/nerve cell marker-positive cells to the BrdU-positive cells/nerve cell marker-negative cells among the NC, overexpressed miR-124 and si-PDXK groups. BrdU, bromodeoxyuridine; MAP2, microtubule-associated protein 2; miR-124, microRNA-124; NC, negative control; NF, neurofilament; NSE, neuron-specific enolase; si-PDXK, PDXK-siRNAs. *P<0.05 compared with the NC group.