Table 4 Genotype frequencies of IL28B SNPs in normal controls and patients with chronic HCV infection, SVR positive, SVR negative

From: IL28B genetic variations are associated with high sustained virological response (SVR) of interferon-α plus ribavirin therapy in Taiwanese chronic HCV infection

Clinical	SVR positive			SVR negative			HCV			Normal
characteristic/ IL28B SNPs	Male (N=360)	Female (N=199)	Total (N=559)	Male (N=83)	Female (N=86)	Total (N=169)	Male (N=443)	Female (N=285)	Total (N=728)	Male (N)^a	Female	Total
rs12980275
AA	0.903	0.950	0.920	0.807	0.791	0.799	0.885	0.902	0.892	0.870	0.883	0.876
AG	0.097	0.045	0.079	0.193	0.209	0.201	0.115	0.095	0.107	0.127	0.112	0.120
GG	0.000	0.005	0.002	0.000	0.000	0.000	0.000	0.004	0.001	0.004	0.005	0.004
rs8105790
CC	0.000	0.000	0.000	0.012	0.000	0.006	0.002	0.000	0.001	0.004	0.002	0.003
CT	0.094	0.045	0.077	0.205	0.186	0.195	0.115	0.088	0.104	0.101	0.105	0.103
TT	0.906	0.955	0.923	0.783	0.814	0.799	0.883	0.912	0.894	0.895	0.892	0.894
rs11881222
AA	0.911	0.960	0.928	0.795	0.791	0.793	0.889	0.909	0.897	0.881	0.892	0.886
AG	0.089	0.040	0.072	0.193	0.209	0.201	0.108	0.091	0.102	0.115	0.106	0.111
GG	0.000	0.000	0.000	0.012	0.000	0.006	0.002	0.000	0.001	0.004	0.002	0.003
rs8103142
CC	0.000	0.000	0.000	0.012	0.000	0.006	0.002	0.000	0.001	0.006	0.002	0.004
CT	1.000	1.000	1.000	0.988	1.000	0.994	0.998	1.000	0.999	0.994	0.998	0.996
TT	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000
rs28416813
CC	1.000	1.000	1.000	0.998	1.000	0.994	0.998	1.000	0.999	0.914	0.998	0.953
CG	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.082	0.000	0.044
GG	0.000	0.000	0.000	0.012	0.000	0.006	0.002	0.000	0.001	0.004	0.002	0.003
rs4803219
CC	0.917	0.960	0.932	0.807	0.791	0.799	0.896	0.909	0.901	0.88	0.881	0.883
CT	0.083	0.040	0.068	0.193	0.209	0.201	0.104	0.091	0.099	0.115	0.119	0.117
TT	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000
rs12979860
CC	0.917	0.960	0.932	0.795	0.779	0.787	0.894	0.905	0.898	0.885	0.892	0.888
CT	0.083	0.040	0.068	0.193	0.221	0.207	0.104	0.095	0.100	0.109	0.105	0.107
TT	0.000	0.000	0.000	0.012	0.000	0.006	0.002	0.000	0.001	0.006	0.002	0.004
rs8099917
GG	0.000	0.000	0.000	0.012	0.000	0.006	0.002	0.000	0.001	0.043	0.002	0.024
GT	0.092	0.045	0.075	0.217	0.174	0.195	0.115	0.084	0.103	0.060	0.103	0.080
TT	0.908	0.955	0.925	0.771	0.826	0.799	0.883	0.916	0.896	0.897	0.895	0.896
rs7248668
AA	0.000	0.000	0.000	0.012	0.000	0.006	0.002	0.000	0.001	0.004	0.002	0.003
AG	0.092	0.035	0.072	0.169	0.221	0.195	0.106	0.091	0.100	0.098	0.097	0.097
GG	0.908	0.965	0.928	0.819	0.779	0.799	0.892	0.909	0.898	0.899	0.901	0.900
rs10853728
CC	0.653	0.714	0.674	0.554	0.547	0.550	0.634	0.663	0.646	0.678	0.676	0.678
CG	0.319	0.261	0.299	0.349	0.430	0.391	0.325	0.312	0.320	0.281	0.294	0.287
GG	0.028	0.025	0.027	0.096	0.023	0.059	0.041	0.025	0.034	0.041	0.029	0.036

Abbreviations: HCV, hepatitis C virus; SNP, single-nucleotide polymorphism; SVR, sustained virological response.
^a Normal male (N=514, 514, 514, 514, 514, 514, 514, 513, 514, 513, 513); normal female (N=445, 446, 444, 446, 446, 446, 446, 446, 422, 445); normal total (N=959, 960, 958, 960, 960, 960, 959, 960,935, 958).

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Table 4 Genotype frequencies of IL28B SNPs in normal controls and patients with chronic HCV infection, SVR positive, SVR negative

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