Table 3 Evidence for MS risk myeloid transcription factors regulated by VDR
MS risk myeloid transcription factor | Myeloid cell in which expressed | VDR | BATF | |
|---|---|---|---|---|
VDR Peak | VDR motif | BATF motif | ||
BCL10 | CD14 | No | No | No |
BATF | DC1, DC2 | No | No | No |
HHEX1 | CD14 | No | No | No |
IRF8 | All | Yes | Yes | Yes |
MAF | CD14, DC1 | No | No | No |
NFKB1 | DC2 | Yes (DC1 only) | No | Yes |
POU5F1B | DC1, DC2 | No | No | No |
STAT3 | DC1, DC2 | Yes | Yes | Yes |
STAT4 | DC2 | Yes | Yes | Yes |
ZBTB46 | CD14, DC2 | No | No | No |
ZFP36L1 | CD14 | Yes | Yes | Yes |
ZNF438 | All | Yes | Yes | Yes |
ZMIZ1 | CD14, DC1 | Yes | Yes | Yes |
ZFP36L2 | All | No | No | No |
